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Palmitoyl Tetrapeptide-3/Palmitoyl Tetrapeptide-7
Palmitoyl Tetrapeptide-3 is used to counteract skin slackening and to perk
up and increase the firmness of the fragile skin area around eyes. It decreases
imitation that could lead to puffiness. It is classed as a protein and is used as a

miscellaneous skin-conditioning agent.


Palmitoyl Tetrapeptide-3 is a synthetic peptide comprised of four amino
acids that is used in beauty products and cosmetics to suppress the production of
excess interleukins, the chemical messengers which trigger the body’s acute
inflammatory response. This can lead to glycation damage, or the process by
which glucose links with proteins and causes them to bind together, stiffening
tissues. This negatively affects the skin's support system, comprised of collagen,
elastin and other proteins, and leads to wrinkles, sagging, and uneven skin tone .
Studies have shown that Palmitoyl Tetrapeptide-3 can slow or suppress the
production of excess interleukins, therefore inhibiting unnecessary inappropriate
inflammatory responses and glycation damage. In vitro, scientists found that
"Palmitoyl Tetrapeptide-3 induced a marked dose-dependent reduction in
interleukin production. The higher the concentration of Palmitoyl Tetrapeptide 3,
the greater the reduction in interleukin production – up to 40%." UV radiation is
also known to accelerate interleukin production. Cells exposed to UV radiation
and then treated with Palmitoyl Tetrapeptide-3 saw an 86% reduction of

interleukin production.


Palmitoyl Tetrapeptide-3 is a key ingredient in Matrixyl 3000 (Matrixyl®
3000 based on two peptides: a palmitoyl tripeptide and a palmitoyl tetrapeptide.)
and is used in conjunction with Pal-GHK.Together, they can boost the growth of
the connective tissues and naturally increasing the production of collagen in the
skin; when the production of collagen is increased, the skin can heal and
rejuvenate itself.

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